allosteric in a sentence

1) The activity of many enzymes is regulated by allosteric effectors.

2) A good example is the allosteric regulation of the glycolytic pathway.

3) These simple molecular mechanisms account for the integrative properties of allosteric enzymes.

allosteric example sentences

4) Allosteric enzymes are usually under the simultaneous control of several allosteric effectors.

5) Allosteric enzymes are usually under the simultaneous control of several allosteric effectors.

6) The second form of "non-competitive antagonists" act at an allosteric site.

7) F-2,6-BP is an allosteric regulator of cellular glucose metabolism pathways.

8) Thus, the relevance of ATP as an allosteric effector is questionable.

9) Such targets are called allosteric modulators.

10) Allosteric control occurs as feedback inhibition by palmitoyl-CoA and activation by citrate.

11) Piracetam is a positive allosteric modulator of the AMPA receptor.

12) Often present are allosteric enzymes capable of sensing and responding to concentrations of regulatory species.

13) This may be accomplished by binding to the active site or the allosteric site.

14) These new insights also have implications in understanding allosteric effects and developing new medicines.

15) Regulation by phosphorylation occurs mostly in mammals, while allosteric regulation occurs in most organisms.

example sentences with allosteric

16) Allosteric sites are sites on the enzyme that bind to molecules in the cellular environment.

17) It integrates a textbook example of an extremely fast enzyme with allosteric regulation of enzyme activity.

18) ATP competes with AMP for the allosteric effector site on the PFK enzyme.

19) Alcohol acts as a positive allosteric modulator of GABA receptors, specifically type GABAA.

20) A common drug, diazepam, acts as an allosteric enhancer at this binding site.

21) Cannabidiol also acts as an allosteric modulator of the mu and delta opioid receptors.

22) In this typical example, the allosteric enzyme can be thought of as a switch.

23) This type of regulation often involves allosteric regulation of the activities of multiple enzymes in the pathway.

24) The principal mechanism of action of barbiturates is believed to be positive allosteric modulation of GABAA receptors.

25) Several properties of PPI such as allosteric sites and hotspots, have been incorporated into drug-design strategies.

26) Such an enzyme is said to be ' allosteric ': it can exist in two forms.

27) The repressor gene, lacI, will produce the repressor protein LacI which is under allosteric regulation.

28) Ketamine appears to inhibit the NMDAR by binding both in the open channel and at an allosteric site.

How to use allosteric in a sentence

29) This is because ethanol's effects on these channels are a summation of positive and negative allosteric modulatory actions.

30) The idea of using a positive allosteric agent such as propofol to unmask or enhance GABA effects is innovative.

31) Many metabolic pathways in the cell are inhibited by metabolites that control enzyme activity through allosteric regulation or substrate inhibition.

32) Lanthanum acts at the same modulatory site on the GABA receptor as zinc- a known negative allosteric modulator.

33) It also binds to the allosteric site of the serotonin transporter, similarly, but less potently than escitalopram.

34) Allosteric interactions can both inhibit and activate enzymes and are a common way that enzymes are controlled in the body.

35) Enzymes that are subject to this form of regulation are often multimeric and have allosteric binding sites for regulatory substances.

36) The control of enzyme function by allosteric mechanisms is considered together with an appreciation of the significance of sigmoid kinetics.

37) Pain a entered alkanes can be awarded in specific allosteric codeine with study of first chlorpromazine, cheap online cialis.

38) With respect to PFK1, fructose 2,6-bisphosphate and ADP are examples of metabolites that are allosteric activators.

39) Direct inhibitors of ATP binding or allosteric inhibitors of either ATP binding or ATPase activity can block Hsp90 function.

40) Another tool that generates full reaction networks from a set of rules is the allosteric Network Compiler (ANC).

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