astrogliosis in a sentence

1) HD causes astrogliosis and loss of medium spiny neurons.

2) A few of the most important effects of astrogliosis are listed below.

3) Other histological changes include astrogliosis and the absence of an inflammatory reaction.

4) astrogliosis may also be attenuated by inhibiting the microgliosis response.

astrogliosis example sentences

5) In addition, evidence suggests microglial regulation of astrogliosis may also include inhibitory effects.

6) One notable microglial activation inhibitor is minocycline, which is a known suppressor of astrogliosis.

7) Unlike the microglial response, which occurs rapidly, the start of astrogliosis is often delayed.

8) Late stages of ALS are also characterized by significant astrogliosis and astrocyte proliferation around areas of degeneration.

9) Glial scar formation (gliosis) is a reactive cellular process involving astrogliosis that occurs after injury to the Central Nervous System.

10) Generally, the effects of astrogliosis vary with the context of the initial CNS insult and also with time after the injury.

11) Ultimately, the astrocytes form a dense web of their plasma membrane extensions that fills the empty space generated by the dead or dying neuronal cells (a process called astrogliosis).

12) Rather, therapeutic strategies for minimizing the contribution of astrogliosis to CNS pathologies must be designed to target specific molecular pathways and responses.

13) In addition, the ability of reactive astrocytes to degrade extracellular Αβ deposits may suggest that astrogliosis may affect the progression or severity of AD.

14) In all instances of gliosis resulting from CNS trauma, the long-term clinical outcome is highly dependent on the degree of astrogliosis and scar formation.

example sentences with astrogliosis

15) Notably, unlike astrogliosis, microgliosis is a temporary and self-limited event, which generally lasts only one month after injury, even in cases of extreme damage.

16) It is these changes in astrogliosis which allow the process to be complex and multifaceted, involving both a gain or loss of function as well as both beneficial and detrimental effects.

17) Changes in astrogliosis are regulated in a context-dependent fashion, and the signaling events which dictate these changes may modify both their nature and severity.

18) Changes in astrocyte function or morphology which occur during astrogliosis may range from minor hypertrophy to major hypertrophy, domain overlap, and ultimately, glial scar formation.

19) Traditionally, astrogliosis has been defined as an increase in intermediate filaments and cellular hypertophy as well as an increase in the proliferation of astrocytes.

20) Like other forms of gliosis, astrogliosis accompanies traumatic brain injury as well as many neuropathologies, ranging from Amyotrophic Lateral Sclerosis to Fatal Familial Insomnia.

21) The final component of gliosis is astrogliosis, the proliferation of surrounding astrocytes, which are the main constituents of the glial scar.

22) In the brain, "B. burgdorferi" may induce astrocytes to undergo astrogliosis (proliferation followed by apoptosis), which may contribute to neurodysfunction.

23) Microglial regulation of astrogliosis","Class":"{col0 coll}"}],"Right":[],"TokenNum":1153160801}

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