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binding affinity in a sentence


1) Bold text indicates that binding affinities for cloned human receptors is unavailable.

affinity collocations
2) Furthermore, the ionizable group is favorable for the binding affinity .

3) One mechanism that affects timing is the quantitative binding affinity of transcription factors.



binding affinity example sentences

4) Binding affinity means how tightly cyclic nucleotides bind to the channel.

5) GAT, are often used for their superior binding affinity and specificity.

6) Aluminum and fluorine have the highest binding affinity .

7) It had highly increased binding affinity but was only active when administered intravenously.

8) Compound 4 had no CYP2D6 activity while preserving excellent binding affinity and antiviral activity.

9) Phosphocellulose chromatography utilizes the binding affinity of many DNA-binding proteins for phosphocellulose.

10) For agonists, a highly significant linear correlation was observed between binding affinity and lipophilicity.

11) Molecular mechanics methods may also be used to provide semi-quantitative prediction of the binding affinity .

12) The exploratory implementation of APTES is motivated by its appreciable binding affinity for carbon nanomaterials.

13) The binding affinity of a chelating system depends on the chelating angle or bite angle.

14) An immunosensor utilizes the very specific binding affinity of antibodies for a specific compound or antigen.

15) This changes the charge or sterically hinders the antibiotic, decreasing its ribosomal binding affinity .



example sentences with binding affinity

16) The sulfides showed in most cases at least 2-fold higher binding affinity than corresponding sulfones.

17) DSF can provide information on binding affinity of inhibitors by way of the melting temperature Tm.

18) Other limitations include concerns regarding binding affinity and specificity, in vivo stability, and uptake into cells.

19) Since the binding affinity is determined by the sum of enthalpic and entropic c. Ben using Youtube.

20) One typical problem in cheminformatics is to predict the binding affinity of drug molecules to a given target.

21) Annexin A-II can bind PIP2 in the cell membrane in vivo with a relatively high binding affinity .

22) The relative timing of expression of different genes is due in part to different binding affinity for transcription factors.

23) The relative binding affinities of the two conformations for the substrate largely determines the net direction of transport.

24) Substitution on the amino group with three different amides increased the binding affinity where methylamide had the highest binding.

25) It has the lowest binding affinity for phytate, but present in the largest amount in feed for poultry.

26) These 3150 peptides will be produced synthetically and their binding affinity to the relevant HLA molecules will be tested.

27) The RES binding sight is known to be hydrophobic, and this is thought to contribute to ligand binding affinity .

28) The difference in cysteine-rich repeats between the members of the LDL receptor family lead to the differences in binding affinity .



How to use binding affinity in a sentence

29) One example would be to increase the binding affinity of a small-molecule inhibitor to an enzyme pocket containing aromatic residues.

30) A free, open-source software package for protein design and prediction of mutation effects on protein-folding stabilities and binding affinities .

31) Ranking compounds is far more difficult, and predicting absolute binding affinities is a very distant, currently unachievable third goal.

32) Heparan sulfate proteoglycans (HSPG) may play an important role in the modulation of the different FGFs binding affinities .

33) It has been stated that Ala-replacement of His197 decreases the binding affinity of CP-96345 for the NK1 receptor.

34) All peptides were initially tested at 4&mgr;M concentration, and those found to bind titrated to estimate binding affinities .

35) Hydroxyflutamide is a more potent AR antagonist than flutamide "in vivo", with higher binding affinity for the AR.

36) These modified nucleobases exhibit tunable electronic properties, sizes, and binding affinities that can be optimized for a specific metal.

37) Compared to cyproterone acetate, spironolactone is considerably less potent as an antiandrogen by weight and binding affinity to the androgen receptor.

38) Whilst purification is not necessary for multitarget ELISA, it is essential for measuring binding affinity by plasmon resonance and DNase footprints.

39) Several reagents were tested for the recovery of Con A by desorption which had higher binding affinities to Con A than maltose.

40) Afucosylation is an important CQA for antibodies, which can be vulnerable to its binding affinity toward Fcγ receptors on effector cells.



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